This document is the final regional Plan of Work for 2019-2022 of the European Union for Environment programme (EU4Environment). It consolidates the activities identified for implementation at the regional level with respect to the proposals specified in the Description of the Action (DoA) for Results 1-3 and 5. The document does not include the work plan for Result 4, led by the World Bank, due to administrative procedures around the signatory contract between the European Commission and the World Bank, which made it difficult to conduct all the necessary country consultations and preparatory technical work. The work plan for Result 4 will be added after the completion of the contractual procedure. It builds on initial commitments discussed at the EU4Environment national launch events in six EaP countries (March-April 2019) and the follow-up consultations, including mapping exercise, and discussions at the EaP Panel on Environment and Climate Change (27 May 2019, Vienna) and at the EU4Environment Inaugural Regional Assembly meeting (27-28 June 2019, Brussels). It also takes into account the final comments received by 6 September 2019. It accommodates, to the extent possible, the country requests taking into account feasibility and the resources available.